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What Level of HEPA Filter Efficiency is Used in Laminar Air Flow Systems?

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Laminar air flow systems typically use HEPA filters with an efficiency of 99.97% at 0.3 microns. This implies that the filter can remove about 99.97% of airborne particles that are 0.3 micrometers, which is considered the most penetrating particle size. Laminar air flow systems are an integral part of laboratories, manufacturing units of pharmaceutical companies, …

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Is A PCR Workstation Mandatory for NABL-Accredited Labs?

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A PCR workstation is not legally mandatory for NABL-accredited laboratories. However, it is highly recommended for labs performing PCR-based molecular testing. According to guidelines of NABL and ISO15189, laboratories need to maintain contamination-controlled environments for molecular diagnostics. A PCR workstation NABL help meet these conditions, making it an important component in many in several NABL-compliant …

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Which Lab Drying Method Best Preserves Biological Samples?

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Preserving biological samples during drying is a critical step in diagnostics and research labs. Choosing a wrong drying method can degrade RNA or DNA and compromise the sample integrity. Here is a comparison of common lab drying methods and explains which option is best for sensitivity, tolerance, and research goals: Why drying Methods Matter for …

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How Laminar Air Flow Is Used in Tissue Culture Labs: Step-by-Step Process

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How do laminar airflow cabinets work in tissue culture labs? Learn a step-by-step process to maintain sterility, prevent contamination, and improve lab safety. A laminar air flow cabinet is widely used in tissue culture laboratories to maintain a sterile working environment. It works by passing air through HEPA filters to remove dust, contaminants, and microbes …

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Common Reasons Biosafety Cabinets Fail Containment Tests and How to Fix Them

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Table of Contents Biosafety cabinets fail containment tests due to improper airflow balance, damaged HEPA filters, poor installation, or inadequate maintenance. Regular certification, proper placement, and timely replacement of filters help restore the performance of the equipment and ensure safe handling of hazardous biological materials in laboratories. A BSC is one of the most crucial …

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How to Choose an Electrophoresis Power Supply for Molecular Biology Labs?

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Electrophoresis is one of the basic techniques in molecular biology laboratories used to separate DNA, RNA, and proteins based on size and charge. While gels, buffers, and chambers receive maximum attention, power supply is that component that directly controls accuracy, reproducibility, and safety. Read this guide to understand the significance of power supply for electrophoresis …

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Gel Electrophoresis: DNA vs RNA vs Protein Differences Explained

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Gel electrophoresis results in the separation of DNA, RNA, and proteins based on different principles. DNA and RNA separation takes place based on size by using agarose or polyacrylamide gels. On the other hand, protein separation occurs based on size and charge using SDS-PAGE or native PAGE. Each method uses specific buffers, stains, and conditions …

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Vacuum Oven vs Hot Air Oven: Which Is Better for Heat-Sensitive Samples?

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Ovens play a crucial role in research facilities, laboratories, and industrial settings for drying, curing, and heat treatment processes. However, when working with heat-sensitive samples, choosing the right equipment becomes important. Among the choices are vaccum ovens and hot air ovens. While both serve heating purposes, the operating principles and impacts on delicate samples differ …

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What Temperature Uniformity Is Required in a Laboratory Water Bath?

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Most laboratory water baths need to maintain temperature uniformity within two to five degrees Celsius across the chamber. High-precision applications such as molecular biology or enzymatic reactions may require uniformity as accurate as 0.1 degree Celsius. However, routine tasks like sample warming can tolerate slight variations. What is Temperature Uniformity? Typically, temperature uniformity is all …

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Which Samples Require Ultra-Low Temperature Freezer Storage?

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Ultra Low Temperature or ULT freezers play a crucial role in laboratories, hospitals, and research facilities across the world. They are designed to maintain a temperature range of -40 degrees Celsius and -80 degrees Celsius and preserve highly sensitive chemical samples and biological samples that would degrade at standard freezing temperatures. These samples are usually …

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